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In a broader sense, neurotoxicity may refer to a permanent or reversible adverse effect of a substance on neuronal structure/function that induces disruption of neuronal components, collapse of entire neurons, histologic signs of neuronal injury, and/or behavioral abnormalities (Moszczynska and Callan, 2017)

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Although the analytical method used in this study did not possess the power to detect species-level changes, the observed decrease in Clostridium subcluster 4 was verified by two independent methods