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Since TLR4 + ILC2s were absent in the bronchial epithelial layer, whereas MUC5AC was localized to goblet cells within the surface epithelium, suggesting that TLR4 + ILC2s indirectly regulate mucus secretion likely via IL-13 (Supplementary Fig

Takeda, S

ACNs exhibit a dual role in regulating ROS levelsproviding protection in OP, RA, and OA by reducing ROS levels, while exerting anticancer effects in OS by elevating ROS levelsdue to differences in cellular redox sensitivity, target cell types, and activated signaling pathways across various environments

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In addition, BD patients, especially at a late stage, show decreased responsiveness of glucocorticoid receptors [164]

.PadyukovLGenetics of rheumatoid arthritis.2022;44(1):4762
