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Additionally, considering that the amino acids whose concentrations were increased in the group administered 1000 mg/kg Ltheanine were Glu, Gln, Leu, Ser, Met, Gly, Val, and Lys, it was suggested that although Ltheanine is reabsorbed by amino acid transporters such as ASCT2 and EAAC1, which use the amino acids whose excretion was increased as transport substrates, the specificity of the transporter is not high (Avissar et al

doi: 10.3390/molecules23020272

Li W, Sun Z, Chen C, Wang L, Geng Z, Tao J

However, excessive ROS production has been detected in tumorigenesis and malignant progression

10 Reduced glutathione is associated with higher oxidative stress, 11 which contributes to damage 12 in the trabecular meshwork cells and retinal ganglion cells, worsening glaucoma and accelerating optic nerve damage

Careful control of these parameters can modulate the interactions between nanomaterials and biological tissues, including their penetration, diffusion, absorption, distribution, immune recognition, retention time in organs, and systemic clearance, thereby minimizing unintended toxic effects (176)