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The intermittent dosing solution is notable: when researchers alternated MT-2 infusion with off-periods, each reapplication produced a full anorectic response

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The evidence for this is mainly based on the observed significant antiallodynic and antihyperalgesic effects of GAT-1 inhibitors in rodent models of CIPN

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widest below the middle and tapering at both ends) the leaf blade is linear (very narrow with more or less parallel sides) the leaf blade is oblong (rectangular but with rounded ends) the leaf blade is obovate (egg-shaped, but with the widest point above the middle of the leaf blade) the leaf blade is ovate (widest below the middle and broadly tapering at both ends) the leaf blade is spatulate (spoon-shaped