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Despite its beneficial roles, excessive production of NO can lead to its reaction with superoxide to form peroxynitrite (ONOO ), a potent oxidizing and nitrating agent [31]

The liver, the body's primary detox organ, relies heavily on glutathione to process and eliminate toxins, including heavy metals, pollutants, and metabolic waste products

The Parkinson disease-associated A30P mutation stabilizes -synuclein against proteasomal degradation triggered by heme oxygenase-1 over-expression in human neuroblastoma cells

[82] Lateral hypothalamic orexin neurons innervate every component of the ascending reticular activating system (ARAS), which includes noradrenergic, dopaminergic, histaminergic, and serotonergic nuclei that promote wakefulness

However, endogenously produced H 2 S can be hydrolyzed to hydrosulfide and sulfide ions

Severe consequences like diminished absorption of nutrients, synthesis of vitamins and non-essential amino acids, and accelerated risk of obesity, asthma, diabetes, and infections