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Description
Role: Co-Investigator

The Global Substance Registration System (GSRS)

In the liver, it neutralizes toxic substances and eliminates them from the body

However, prolonged or intense physical activity can deplete intracellular GSH levels because GSH is oxidized to its disulfide form, glutathione disulfide (GSSG), during ROS detoxification [69,70]

In APP/PS1 mice, subcutaneous injection of 27-OHC increased gene and protein expression of APP, BACE1, and receptor for advanced glycation end products (RAGE), while decreasing expression of a disintegrin and metalloprotease 10, LRP1, and insulin-degrading enzyme (IDE) (Zhang et al., 2019)

Cell And Mol Life Sci
