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Role of copper transporters in copper homeostasis
Lancet 2000;356:1423-30
211 However, the potential value of vitamin A supplements in pregnant women with HIV remains questionable, particularly as some studies have indicated that vitamin A supplementation may increase the HIV load in breast milk 212 and may potentially elevate the risk of HIV transmission from mother to child

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These insights have laid the groundwork for novel therapeutic paradigms where riboflavin acts synergistically with genetic correction or as a pharmacological cofactor to enhance the folding, stability, and activity of mutant flavoproteins

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