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NAD+ also acts as a required cofactor for non-redox NAD+-dependent enzymes, especially sirtuins and poly(ADP-ribose) polymerases (PARPs) [2]

This helps researchers move from compound-specific review into broader pathway comparison without leaving the core research archive

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While studies on the therapeutic effects, pharmacokinetics, and toxicology of BPC157 have been completed [10, 11], its molecular mechanisms remain elusive