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This review examines recent human studies (20202025) to explore how microbiota-derived TMAO, miRNA regulatory networks, and changes in the oral microbiome contribute to the development of atherosclerosis and myocardial infarction

Tudor, M., Akbarian, S., Chen, R

1 (2016): 20391, 10.1038/srep20391

Wang et al., 2020)

242 Two independent cohort studies found that patients with dyslipidemia experienced a decrease in plasma TMAO levels after initiating statin treatment, but TMAO levels returned to baseline after a four-week discontinuation of the medication

This pearl is partly based on findings from a retrospective review of 160 patients who took one course of isotretinoin compared with 82 patients who underwent two courses