glutathione degradation ferroptosis L-2-Hydroxyglutarate sensitizes through ATF3/CHAC1-mediated in hepatocellular carcinoma The Ferroptosis Pathway
Description
This indicates that ferroptosis is essential for health maintenance via regulating metabolic and redox balance, as well as being implicated in the development and treatment of multiple human diseases 12,13,14 (Fig
10.1242/dev.00448 22 DasGuptaR.FuchsE
10.1002/cac2.12231 82 MengZ.LiangH.ZhaoJ.GaoJ.LiuC.MaX.et al (2021)
The glutathione binds with these substances and helps the liver transform them into a form that can be safely excreted through urine or bile
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PMID: 6355946
