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5 Advantages and limitations of brain organoids for drug screening of mitochondrial diseases with neurodevelopmental manifestations 5.1 Advantages Restore the lack of physiological neural models: Recapitulate human neural networks, functions and cytoarchitecture of specific regions of the brain

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Indeed, PD-1 binding in activated human T cells downregulates both glycolysis and glutaminolysis while significantly increasing their SRC (125)