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Given these tight and crucial metabolic crosstalks between tumor cells and the immunologic compartment, it can be envisioned that targeted therapies are accompanied by metabolic-based treatments hitting both neoplastic and environmental cells in order to overcome potential cancer resistance (e.g

Solution NMR structure of the C-terminal domain of the human protein DEK

Approximately three times the amount of rutin was identified in asparagus cladophyll compared to the green asparagus stem.[14] It was reported that asparagus bottom-stems contain protodioscin, an antitumor substance, at a level over 100 times that seen in the green asparagus stems.[15] These findings indicate that the by-products of asparagus, such as cladophyll and bottom-stem, could be used as the sources of several functional ingredients for supplements to improve metabolic syndrome, which is characterized by hypertension, hyperglycemia, and dyslipidemia

M.KangN.BienenstockJ.FosterJ

doi:10.1016/j.jaci.2012.03.042 Wantke F, Gotz M, Jarisch R

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