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PYRIN senses bacterial toxins that modify and inactivate Rho GTPases, and PYRIN dephosphorylation and microtubule polymerization are thought to participate in inflammasome assembly [308]

Informed consent was obtained from the patients, and the study protocol was approved by the Ethics Committee of the Second Affiliated Hospital, Zhejiang University School of Medicine (Permit number: 2024-1360)

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Suicidal and vital NETosis differ in their activation pathway and the nature of the stimulation

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Neuroscience 335:207220 Mosley RL, Benner EJ, Kadiu I, Thomas M, Boska MD, Hasan K, Laurie C, Gendelman HE (2006) Neuroinflammation, oxidative stress and the pathogenesis of Parkinsons disease