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Since the drug will be given as an intravenous infusion, F = 1

Recombinant human IGF-1, given over 6 months at a dose FDA-approved for long-term treatment of growth failure in children with severe primary IGF-1 deficiency, reduced coronary artery atherosclerosis and promoted a stable plaque phenotype in a pig model of familial hypercholesterolemia (FH) (148)

Think of them as gentle growth-signal boosters

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[14] reported that the oral administration of -EC increased neuronal GSH levels in a mouse model of AD, consequently reducing neurodegeneration and ameliorating cognitive decline

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